The definitive marijuana guide from Cannabis UK
Quantitative analysis of cannabinoids in commercially
available cannabis seeds
by
Matsunaga T, Watanabe K, Yoshimura H, Yamamoto I
ABSTRACT
delta 9-Tetrahydrocannabinol (delta 9-THC), cannabinol, cannabidiol and
cannabichromene were detected in commercially available cannabis seeds by silica
gel TLC and gas chromatography. These cannabinoids existed in rather high
content (0.10-2.02 mg/100 g of seeds) in the feed for birds especially bracts
(82.3-441 mg/100 g). When the suspension prepared from the benzene washing
solution of cannabis seeds, BenW, was administered at a dose of 3 mg/kg
corresponding to delta 9-THC into a mouse, i.v., BenW caused hypothermia,
catalepsy, pentobarbital-induced sleep prolongation and suppression of locomotor
activity. These pharmacological activities of BenW were significantly higher
than those of delta 9-THC (3 mg/kg, i.v.). These results may indicate the
necessity to reconsider the present regulations on marihuana.
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